Circulatory Drugs

ent ways to produce Coombs serum are described with little or no attempt to define how important they are in the overall scheme of human blood and serum groups. But perhaps because this is a reference book it is more important to detail everything than to discuss those areas that the authors deem important. Some subjects, the Lewis, the I, i, and the leukocyte groups, for example, are discussed in less detail than I prefer, but this may be because the bulk of the text is five years old and much information in these areas is of recent vintage. There are excellent chapters on the immunology and the chemistry of blood group substances, good detail about the origins of the isoagglutinins, and subjects like the origin of the blood groups that are rarely so well summarized. I particularly enjoyed the biographical sketches of famous people in the field, and the very nice historical perspective on all subjects. Human Blood and Serum Groups will no doubt be used extensively as a reference source. As such, it is more than adequate. JOSEPH R. BOVE